Decreased CD44 expression may play an important role in promoting lymph node metastasis in IMPC through an inability or decreased capacity to bind with the surrounding stroma. Moreover, high CD44s expression levels in the concurrent ICNST component may be related to the development of IMPC.

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Peritoneal recurrence of breast cancer 10 years or more after initial surgery is very rare. We present a case of peritoneal recurrence occurring 42 years after a left breast mastectomy. The patient presented with abdominal pain and vomiting, and an abdominal computed tomography scan revealed a well-defined, ovoid mass causing intestinal obstruction. Partial resection of the ileum was performed, and the pathological diagnosis of the resected tumor was poorly differentiated adenocarcinoma. In addition, a hard tumor was observed on the left chest wall that was also found to be a poorly differentiated adenocarcinoma. Both tumors were negative for progesterone receptor and human epidermal growth factor receptor 2, but positive for estrogen receptor. A late recurrence of breast cancer was diagnosed, the postoperative course of which was uneventful. This case illustrates that an extended follow-up is required for breast cancer patients to check for late recurrence.

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