The study of companion (pet) dogs is an area of great translational potential, as they share a risk for many conditions that afflict humans. Among these are conditions that affect sleep, including chronic pain and cognitive dysfunction. Significant advancements have occurred in the ability to study sleep in dogs, including development of non-invasive polysomnography; however, basic understanding of dog sleep patterns remains poorly characterized. The purpose of this study was to establish baseline sleep–wake cycle and activity patterns using actigraphy and functional linear modeling (FLM), for healthy, adult companion dogs. Forty-two dogs were enrolled and wore activity monitors for 14 days. FLM demonstrated a bimodal pattern of activity with significant effects of sex, body mass, and age; the effect of age was particularly evident during the times of peak activity. This study demonstrated that FLM can be used to describe normal sleep–wake cycles of healthy adult dogs and the effects of physiologic traits on these patterns of activity. This foundation makes it possible to characterize deviations from normal patterns, including those associated with chronic pain and cognitive dysfunction syndrome. This can improve detection of these conditions in dogs, benefitting them and their potential as models for human disease.
Aimed to the social risk appraise of construction project, the qualitative and quantitative analysis, as well as the theory and empirical research methodologies are used in this paper, and taking a Demolition and Relocation Project of Guangzhou as the Study Case. Based on questionnaire investigation and depth interview to the samples of reference groups in this project, the potential social risk and the real appeals of the reference groups are described systematically and objectively in this paper. In the mean time, the SPSS software is used to analyses the statistical data. Finally, focused on above analysis, the relevant suggestions to prevent the social risk are proposed. Appraising conclusion shows that most sensitive people, within the scope of demolition, agree on the quasi decision-making matters on the construction project, and at least, they are not opposed to it. However, there are several practical issues to which we need to pay close attentions and to require proper solutions. Before these issues are solved, suspending the demolition is suggested.
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