Functional dyes with a chromeno[b]quinoline
skeleton
(3a–d) were synthesized by one-step
cyclization between coumarin derivatives and aromatic amines under
the promotion of anhydrous aluminum chloride in 41.2–45.8%
yields. Their maximum absorption and emission wavelengths locate at
358–396 and 420–603 nm with large Stokes shifts (168–231
nm), and their intramolecular charge transfer has been corroborated
by density functional theory calculations. Cell experiments have proved
that the probes 3a–c possess the
ability to target lipid droplets.
As an alkaloid, quinazolinone exhibits excellent biological properties, structurally, it also has the potential to construct fluorescent probes with conjugated structures. In this work, probes 5a-c and 6b were obtained...
A series of viscosity probes targeting different organelles were obtained using a single hemicyanine dye as the matrix structure. Specifically, probes 1a-d were obtained by introducing four amines (6-amino-2H-chromen-2-one, N-(2-aminoethyl)-4-methylbenzenesulfonamide,...
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