Aiming the potential hazards and risks brought by the analog signal processing module of the vehicle controller, an analog signal processing module based on ISO26262 standard is designed to enhance the safety and reliability of the vehicle controller. Based on the relevant technical design methods in the functional safety standards, this paper performs a hazard and risk assessment on the unexpected acceleration or deceleration of the vehicle caused by the failure of the analog signal processing module, determines that it should achieve the functional safety level ASIL D and functional safety requirements, and then adopted the dual-core principle for redundancy design of the analog signal processing module. The fault injection is carried to simulate the vehicle controller analog signal processing fault. The test and verification results show that the vehicle controller analog signal processing module designed in this paper meets the ASIL D safety level, and the three types of fault injection pass rate are above 99%. It improves the safety and reliability of the vehicle controller.