This study was performed to observe and measure synovial folds of the occipito-atlanto-axial joints and to explore their clinical significance. Two hundred ninety eight occipito-atlanto-axial joints from 30 embalmed cadavers of children and 20 of adults were dissected to find the incidence, quantity, distribution, forms, dimension, and histology of synovial folds. Synovial folds were found in most joints in both groups except for the posterior median atlantoaxial joints. Most of synovial folds were crescent-shaped, distributed on the superior aspects of the anterior median atlantoaxial joints, or in the antero-lateral aspects of the atlantooccipital joints and the lateral atlantoaxial joints. Compared to the adult group, the child group had a higher incidence of synovial folds (72.5% joints). The adult incidence was found to be 58.5%. 54.3% of the synovial folds in child were medium size or large size, but only 30.1% of the synovial folds in adult were medium size and there were no large ones. Microscopically, there were three histologic types synovial folds in these cervical joints, and 78.9% of them belonged to adipose type or fibro-adipose type in child, but only 45.8% belonged to the two types in adult. Our data suggest that the larger synovial folds in children may predispose them to an increased rate of entrapment with resultant edema and subluxation of the associated joint complex. This may be the cause why some cervical spine diseases preferentially take place in children rather than in adult, such as benign paroxysmal torticollis'atlantoaxial rotatory deformity and Grisel's syndrome.
This study was aimed to optimize the extraction process for Salvia miltiorrhiza Bunge polysaccharide using response surface methodology The results showed that four operating parameters including microwave power, microwave time and the particle size had notable effects on the polysaccharide extraction of Salvia miltiorrhiza Bunge. The effects could be ranked in decreasing order of importance as follows:. Microwave power > microwave time > the comminution degree. The optimal extraction parameters were determined as 573.83W of Microwave power and 8.4min of microwave time and 67.51mesh of the comminution degree, resulting in the yield of Salvia miltiorrhiza Bunge polysaccharide of 101.161mg / g. The established regression model describing polysaccharide extraction from as a function of the three extraction parameters was highly significant (R 2 = 0.9953). The predicted and experimental results were found to be in good agreement. Thus, the model can be applicable for the prediction of polysaccharide extraction from Salvia miltiorrhiza Bunge.
Tissue engineering and regenerative medicine have offered promising alternatives for clinical treatments of body tissue traumas, losses, dysfunctions, or diseases, where scaffold-based strategies are particularly popular and effective. Over the...
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.