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The aim of this study was to investigate and compare fluoride release of giomer (Beautifil Injectable), compomer (Dyract ® XP), and composite resin (Filtek™ Z350XT) through adhesive (Scotchbond Multi-Purpose) layer.A total of 20 cylindrical specimens (7 mm in diameter and 2 mm in thickness) of giomer, compomer and composite resin were prepared according to the manufacturers' instruction (10 with adhesive and 10 without adhesive). These specimens were immersed individually in 2 mL of deionized water at 37℃. The amount of fluoride release was measured on the 1 st , 3 rd , 7 th , 14 th , 21 st , and 28 th day. To confirm uniform application of the adhesive layer, additional 18 specimens with adhesive were prepared and evaluated by scanning electron microscope.The giomer and compomer groups with adhesive applied showed no fluoride release until the 3 rd day. However, from the 7 th day, fluoride was detected. The application of dentin adhesive did not completely prevent fluoride release from giomer or compomer. Fluoride release was significantly (p < 0.05) reduced through the adhesive layer. The reduction of fluoride release was more remarkable on the giomer. Abstract 180 Corresponding author : Howon Park Ⅰ. 서 론 불소는 탈회된 치아 경조직의 재광화를 촉진하고 치아의 내 산성을 증가시키며, 미생물의 대사와 성장을 방해하고 세균막의 발육을 저하하는 등 다양한 기전으로 항우식 효과를 나타낸다 [1,2]. 이러한 불소의 효과를 치아 수복물을 통해 얻고자 불소를 방출하는 여러 수복재가 개발되었다. 가장 초기에 개발된 글라 스아이오노머는 느린 경화 반응, 경화 초기의 수분 민감성, 낮은 물성 및 높은 용해도 등의 단점을 보였다[3]. 이러한 단점을 개 선하기 위해 복합레진의 특성을 결합한 레진강화형글라스아이 오노머, 컴포머 등의 재료가 개발되었다. 레진강화형글라스아이 오노머는 경화 초기의 수분 민감성을 극복하였고 치질과의 결합 능력 및 높은 불소 유리능을 유지하였으나 표면활택도와 물리적 성질이 여전히 불량하였다[4]. 레진강화형글라스아이오노머보다 복합레진과 더 유사한 컴포머는 저농도의 불소를 지속적으로 유 리하지만 기대와는 달리 부족한 파절 강도와 전단 강도를 보이 는 등 임상적 활용에 제한이 있었다[5,6]. 최근에는 불소 유리 및 재충전능을 가지는 pre-reacted glass ionomer (PRG) 필러를 함 유한 광중합 레진 제제인 자이오머(Giomer)가 개발되었고 복합 레진과 견줄 만한 물성을 가진다고 보고되었다[7,8]. 불소 유리 수복재의 노출된 표면에서 외부로 유리되는 불소는 인접 치질에 작용하여 항우식 효과를 보이고 타액의 불소농도를 높여 우식의 예방에 도움을 준다[9,10]. 와동의 내부, 즉 접착된 치질에 유리되는 불소 역시 상아질로 침투하여 상아질의 광화를

The purpose of this study was to compare the cariogenicity of commercially available bovine milk and low-fat milk in a biofilm model using the CDC Biofilm Reactor. Streptococcus mutans ATCC 25175 biofilms were formed on saliva coated bovine enamel slabs in a CDC Biofilm Reactor. Biofilms were exposed three times per day to one of the following materials: commercial whole milk (fat content: 3.4%), low-fat milk (fat content: 1%), or 0.9% NaCl. Medium pH was measured at different time points. After 5 days, biofilms were separated from slabs to evaluate the CFUs. The biofilm thickness was observed by confocal laser-scanning microscopy (CLSM). Enamel slab's demineralization was assessed by measuring surface microhardness before and after the experiment. For microhardness and CFUs assessment, no significant difference was found among the three groups. All groups showed similar pattern of medium pH change and biofilm thickness. Our results showed that there was no difference in the cariogenicity between whole milk and low-fat milk. Both milks were relatively non-cariogenic compared to the control group.

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