The previous study reported that Etlingera elatior (Wualae) has activity as immunostimulant with dose at 300 mg/kg BW and 400 mg/kg BW. Formulating natural product into effervescent granule (GE) can increase practicality and interest to consume traditional medicine. This study aims to investigate the immunostimulant activity of Wualae ethanolic extract in the effervescent granule. Wualae was macerated with ethanol then formulated into effervescent granule at dose 300 mg/kgBW and 400 mg/kgBW. Formulations were evaluated. Animals were divided into 4 groups and treated with: group I (positive control); group II (negative control); group III (GE dose at 300mg/kgBW); and group IV (GE at dose 400mg/kgBW) for 7 days and at days 8, groups were infected by Staphylococcus aureus intraperitoneally. Immunostimulant activity was measured by calculating the Specific Phagocytic Activity (SPA) of macrophage. Data collected from the evaluation and measurement of the SPA then analyzed using SPSS. Results from the evaluation were considered good except the moisture content of effervescent granule. Results from SPA was found that effervescent granule at dose 300 mg/kgBW and at dose 400 mg/kgBW have 26.33% and 32.5% consecutively with significance 0.02 (p<0.05). Thus, effervescent granule has comparable phagocytosis activity with positive control.
Penelitian ini bertujuan untuk mengetahui apakah terdapat hubungan stress dengan obesitas pada masa pandemi di SMKN 5 Samarinda. Penelitian ini menggunakan rancangan penelitian kuantitatif dengan metode cross sectional. Jumlah sampel penelitian ini 122 orang menggunakan stratified random sampling. Berdasarkan hasil penelitian, klasifikasi normal yang 33 orang (27.0%), Stres 89 (73,0 %) kemudian hasil obesitas sangat kurus sebanyak 17 orang (13.9%), kurus sebanyak 22 orang (18.0%), normal sebanyak 67 orang (54.9%) dan kategori gemuk sebanyak 6 orang (4.9%) serta kategori obesitas sebanyak 10 orang (8.2%). Setelah dilakukan uji spearman didapatkan hasil bahwa terdapat hubungan yang signifikan dengan kekuatan yang kuat antara variabel stress dengan variabel obesitas pada masa pandemi di SMKN 5 Samarinda. Manfaat dari penelitian ini adalah siswa dapat mengetahui terkait stress yang dapat berdampak pada obesitas.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2025 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.