Our study confirms the high incidence of non-melanoma skin cancer among KTRs in a Mediterranean population with occupational sun exposure and the patient's age at the time of transplantation being the main risk factors. We believe that all organ transplant programs should provide educational information about protecting oneself from the sun as well as include follow-up visits by dermatologists in order to facilitate early diagnosis and treatment of skin cancer.
Clinical spectrum of specific lesions of cutaneous sarcoidosis showed a good correlation with granulomas localization in the biopsies. However, traditional classification of specific cutaneous sarcoidosis is often overlapping. On the other hand, foreign bodies and other atypical histological findings were more common than initially expected.
All cases of MM diagnosed in 23 Hospitals in Catalonia, from 2000 to 2007 were recorded and its incidence calculated and adjusted for the European standard population through the direct method. The age standardized rate varied from 6.74 in 2000 to 8.64 in 2007 for all melanomas and from 4.79 to 5.80 for invasive MMs, the Breslow thickness being stable during the period. The increase in invasive melanoma incidence in the elderly was remarkable, the crude rate increasing from 11.04 (2000) to 15.49 (2007) in the 60–64 yr population, while remaining more stable from 3.97 in 2000 to 4.55 in 2007 for the age range of 30–34 ys or with a tendency to decrease from 5.1 in 2000 to 2.5 in 2007 for age range of 25–29 yr, age ranges much more affected by immigration. Despite the large immigrant population (nearly one million immigrants that arrived in Catalonia during the study period from countries with a low melanoma incidence), melanoma incidence in our region has risen considerably and this trend will likely persist in the near future.
Multicentric reticulohistiocytosis is a rare disorder of unknown etiology, characterized by skin and mucosal papulonodular eruptions and destructive polyarthritis. Histopathological study of these lesions shows a nodular infiltrate composed of histiocytes and multinucleated giant cells, with an eosinophilic, granular, ‘ground-glass’ cytoplasm. We report a case of multicentric reticulohistiocytosis with skin lesions mimicking dermatomyositis and we also review previously reported cases describing such a clinical situation. Our case further emphasizes that multicentric reticulohistiocytosis can mimic clinical features of dermatomyositis. A macular or patch-like erythema in a photodistributed fashion, in addition to other clinical manifestations, can be mistaken for dermatomyositis. However, skin biopsies from these areas may early differentiate both conditions with different treatment options and morbidity.
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