Background and Objectives: Intracranial hemorrhage caused by the rupture of brain aneurysms occurs in almost 10 per 100,000 people whereas the incidence of such aneurysms is significantly higher, accounting for 4–9%.Linking certain factors to cerebral aneurysm rupture could help in explaining the significantly lower incidence of their rupture compared to their presence. The aim of this study is to determine the association between the corresponding circle of Willis configurations and rupture of cerebral aneurysms. Materials and Methods: A group of 114 patients treated operatively for aruptured cerebral aneurysm and a group of 56 autopsied subjects were involved in the study. Four basic types of the circle of Willis configurations were formed—two symmetric types A and C, and two asymmetric types B and D. Results: A statistically significantly higher presence of asymmetry of the circle of Willis was determined in the group of surgically-treated subjects (p = 0.001),witha significant presence of asymmetric Type B in this group (p < 0.001). The changeson the A1 segment in the group of surgically-treated subjects showed a statistically significant presence compared to the group of autopsied subjects (p = 0.001). Analyzing the presence of symmetry of the circle of Willis between the two groups, that is, the total presence of symmetric types A and C, indicated their statistically significant presence in the group of autopsied patients (p < 0.001). Conclusions: Changes such as hypoplasia or aplasia of A1 and the resulting asymmetry of the circle of Willis directly affect the possibility of the rupture of cerebral aneurysms. Detection of the corresponding types of the circle of Willis after diagnostic examination can be the basis for the development of a protocol for monitoring such patients.
Cervical epidural hematoma in children is very rare. Adequate neurological examination, di- agnostics and urgent surgical intervention are of paramount importance for accomplishing good results. Early and persistent rehabilitation are the condition for achieving maximal recovery.
Solitary plasmacytomas are a hematological disorder. They can take the form of solitary bone plasmacytoma (SBP) and the form of solitary extramedular plasmacytoma (SEP). These types tend to become multiple myeloma (MM). Treatment is predominately hematologic and radiation therapy. In most cases, SBP is detected after the destruction of the vertebrae and the occurrence of neurological deficits. It is very important to indicate the appropriate and timely surgical approach before applying further therapeutic procedures. Eight patients in whom it was decided to apply surgical procedure of total tumor resection prior to the application of chemo-and radiation therapy were subjected to analysis. The surgical approach involved the complete removal of altered vertebral bodies with anterior and posterior reconstruction of the spinal column. The primary preoperative and post-operative neurological status was monitored. Removing the corpus which compromises the width of the spinal canal and the removal of the spinal cord pressure allows neurological recovery or the prevention of severe neurological damage resulting from the destabilization of the spinal column. In all cases there was significant neurological improvement. In addition, in cases of SBP of vertebrae, long-term remission or healing is often achieved. Complete removal of solitary plasmacytomes of the vertebrae allows the patient to actively continue with further treatment and the prevention of severe neurological damage. A complete 3D reconstruction of the spinal column and the achievement of its mechanical stability is a prerequisite for achieving neurological stability. A timely surgical intervention is conditioned by quality preoperative diagnostic approach and early detection.
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