The background of this study is Drug selection for PTSD is carefully selected based on experience and evidence. To reduce the hospital drug crisis, P-Drugs must be developed. The goal of personal formulary development is to improve the effectiveness, safety, availability of medicines in decision making. The aim of this study is to develop Personal formulary for post-traumatic stress disorder. Local residents educated and developed PTSD drug kits. Scores were assigned to marketed drugs using 4 parameters provided by Joshi and Jayavikramarajah: efficacy, safety, cost, and convenience of drug groups. Fractions were assigned according to the importance of the drug to give efficacy 0.4, safety 0.3, cost 0.2, and convenience 0.1. The evaluation was done in 4 dimensions from 1 to 10. Taking all the above factors into consideration, the SSRIS group received the highest score and was selected as the most suitable group for developing a personal PTSD formulary. Typically, paroxetine, sertraline, fluoxetine, escitalopram, and citalopram have been prescribed for post-traumatic stress in SSRIS. Among the five drugs, paroxetine has a good value for money. Paroxetine has little effect on other body systems and reduces induced PTSD. Therefore, paroxetine has the highest efficacy and safety. This project has significantly improved the skills of residents by developing a personal form after appropriate discussion in accordance with WHO goals. This will help to promote the rational use of medicines for residents in the future careers as doctors.