A retrospective review of 381 patients with histologically confirmed nasopharyngeal carcinoma referred from all regions of Saudi Arabia to the King Faisal Specialist Hospital and Research Centre during the 10½-year period (June 1975 to December 1985 demonstrated a high frequency of stage IV tumors (93%), with 17.3% having distant metastases at presentation. There was a very low incidence (2%) of keratinizing squamous cell carcinoma, considered due to the relatively young age of the population. Age analysis indicated a peak incidence among the referred cases in the 45-55 age group, with a smaller peak in the 20-24 age group for both males and females, although the younger age peaks were reduced when the patient numbers were standardized for available population census figures.
Fifteen patients with post-circumcision squamous cell carcinoma of the penis are discussed (13 were referred from the southwestern region of Saudi Arabia). Carcinoma developed in circumcision scars on the penile shaft. Excision was the only effective treatment and resulted in disease control in approximately 64 per cent of those treated surgically. Radiation therapy and chemotherapy did not seem to be effective in these patients.
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