Background: Despite considerable advances in our knowledge of the pathophysiology of inhalation injury, there are few specific therapeutic options, and patient care is mainly supportive. Platelets release growth factors and other immune system components to start healing process. By using nebulized Platelet Rich Plasma (PRP), platelets may reduce inflammation and stimulates bronchial tree healing. However, there are no clear data supporting or refuting the use of inhaled PRP in inhalation injury. Objective: To evaluate the role of nebulized autologous Platelet Rich Plasma (PRP) in management of Smoke Inhalation Injury (SII) as early adjuvant therapeutic and prognostic modality.Methods: This is prospective study that included 40 patients with burns 25-50% TBSA and have inhalation lung injury. They were divided into 2 groups; 20 patients received aerosolized particles of nebulized PRP beside regular regimen. The other control group included 20 patients and received regular treatment regimen only.Results: There was a statistical significant difference (p<0.01) of biologic changes in upper airway with smoke injury in study group patients compared to control group patients who received regular protocol measured at the same follow-up time interval, relatively same TBSA and initial bronchoscopy scoring. The mean extubation time was 7±1 days in study group compared to 14±1 days in control group. Study group less showed shorter hospital stay and less mortality rate. Conclusion:The application of aerosolize the PRP solution in the nebulizer with regular treatment protocol of inhalation burn patients could be a beneficial therapeutic tool for regenerating of post burn damaged tracheo-broncho-pulmonary tree. Further studies on larger patient population with clinical and pathological evidences are warranted.
In this study, a cost-effective powdered Zn l-aspartic acid bio-metal organic framework (Zn l-Asp bio-MOF) was reported as an efficient adsorbent for Direct Red 81 (DR-81) as an anionic organic dye.
Background: Fat survival remains a challenge following fat grafting and has been a subject of debate. The key to successful fat grafting in buttock enhancement dictates familiarity with the technique, knowledge of the gluteal topography and aesthetics along with understanding of the patient's desired needs and goals. However, several areas still need to be researched. Objectives: This study aims to describe the anthropometric measurements of the Middle Eastern female buttocks and to evaluate the post-operative volume changes of structural fat grafting following gluteal enhancement procedures. Methods: This study included sixty adult healthy females. Candidates were classified into four main groups; control group (30 candidates) for measuring anthropometrics of Middle Eastern buttocks with normal BMI, and other 30 candidates were grouped into three surgical groups (10 candidates for each) according to the amount of fat grafting. Anthropometric measurements were obtained directly through patients' photos (posterior and lateral views) pre-operatively, 3 and 6 months postoperatively. Pre-operative volume of gluteal region in each quadrant was measured for the whole buttock by using the ultrasound then compared to that of 3 and 6 months post-operatively. Results: Control group (30 candidates) showed that round shape buttocks was the dominant shape. Fat survival rate of fat injected in subcutaneous plane decreased with increasing volume of fat injected, while in the intramuscular plane the survival rate the same and was not affected significantly. Conclusion and Recommendations: Round shaped buttock is the dominant shape in Middle Eastern buttock; fat survival rate is greater when injected intramuscular. We warn surgeons from trying intramuscular fat injection without anticipating problems and also without taking in consideration precautions and recommendations especially in large volume grafting. Also, we recommend authors to perform more studies in Middle Eastern buttocks for more control cases to confirm the anthropometric criteria of Middle Eastern buttocks.
Backgrounds: Many surgical techniques have been described for management of grade III gynecomastia. Nippleareola complex (NAC) free transfer, inferior and superior pedicle techniques have been published in the literatures for treatment of grade III gynecomastia. In order to reduce the excess skin, all theses techniques leave acceptable scars. Original postero-inferior technique was described to improve the aesthetic outcome with preserving the neurovascular pedicle of the areola. This technique maintains the sensitivity and vitality of the new areola, but post-operative rates of breast contour and NAC were still not satisfactory. In this study, we described a new modified postero-inferior technique and compared its functional and aesthetic outcomes to that of the original technique. Aim of this Study:Is to compare the functional and aesthetic outcomes as well as patients' satisfaction of the original and modified postero-inferior pedicle techniques in patients with grade III gynecomastia.Patients and Methods: 12 adult patients suffering from grade III gynecomastia were included in this cohort prospective study. Patients were treated surgically by modified posteroinferior technique. Post-operative aesthetic and functional outcomes, as well as patients' satisfaction were evaluated by patients' questionnaires and compared to that of the original technique.Results: In comparison to the original technique, aesthetic outcome of modified technique showed more patient satisfaction as regards chest contour (Q1) and NAC rating (Q2) with the same rate of patients' satisfaction as regards functional outcomes (nipple sensitivity and parathesia) also both techniques showed postoperative intact vascularity of the new NAC. Rate of complications decreased from 33% in the original technique to 16.7% in the modified technique with 100% post-operative rate of NAC symmetry. Conclusion:The new modified postero-inferior technique improves the post-operative aesthetic outcomes as well as it preserves the same functional outcomes, if compared with that of the original technique.
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