The primary objective of this paper is to investigate the mediation role of port supply chain integration between Human Resource Management (HRM) practices and port performance (PP) in Kingdome of Saudi Arabia. The present study employed partial lest square structural equation modeling technique to analyze the collected data. The study found some positive significant direct relationship between HRP, port supply chain integration (PSCI) and PP. Besides, this study also found some positive and significant relationship between HRP and PSCI. Additionally, the study confirms the mediating role of PSCI between HRP and PP. The study contributes to the literature and to the practice of ports to understand how the process of HRP and PSCI produces better port performance.