An unusual neurological syndrome in an Arab family with five affected siblings, is reported. Autosomal recessive inheritance is suggested by having multiple affected siblings born to phenotypically normal consanguineous parents. Similar to Davison's Pallido‐pyramidal syndrome, they presented with the clinical signs and symptoms of severe parkinsonism as well as evidence of cortico‐spinal tract disease. In addition, they had dementia and supranuclear upgaze paresis. MRI studies showed significant atrophy of the globus pallidus and the pyramids, as well as generalized brain atrophy in later stages. Therapy with levodopa resulted in significant improvement in the extrapyramidal dysfunction. We suggest that this probably represents a new syndrome which is closely related but not identical to the pallido‐pyramidal syndrome.
Myringoplasty is a beneficial procedure in the pediatric population in the hands of a skilled and experienced surgeons. If performed properly, it has a good chance of restoring a child's hearing. However, a large study with a long follow up is warranted in order to come to a definitive conclusion.
Ai ms: to carry out a retrospective analysis of myringoplasty results in children in our institute. Materials and methods: Thirty five children, 9 to 14 years old, who underwent myringoplasty in our hospital between April 2002 and May 2004, formed the study group. Data regarding successful perforation closure, factors influencing success rates and hearing improvement were recorded. Results: Closure of perforation was successful in 30 (85.7%) of the 35 patients. Graft take failure occurred in 5 patients. Audiological improvement was seen in 27 (77%) patients, out of which 23 cases had 10-15 db and 4 cases had 15-20 db air-bone gap. Hearing was found to be worse postoperatively in 3 patients, while no change was noted in the remaining 5 patients. There was no case of profound hearing loss. Conclusion: Myringoplasty is a beneficial procedure in the pediatric population in the hands of a skilled and experienced surgeons. If performed properly, it has a good chance of restoring a child's hearing. However, a large study with a long follow up is warranted in order to come to a definitive conclusion.
Primary mucosal melanoma is an under diagnosed and rare tumor. Subglottic malignant melanoma is the least common of mucosal melanoma. This paper reports a case of a 60-year-old man who presented to the ENT clinic at King Hussein Medical Center in 2015 complaining of shortness of breath and stridor. Fibro optic endoscopic examination revealed a subglottic mass, microlaryngoscopy and biopsy with immunohistochemical staining revealed the diagnosis of malignant melanoma. The patient was treated by surgical excision followed by radiotherapy.
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