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26A study was conducted to investigate the accumulation and distribution of arsenic in 27 different fractions of rice grain (Oryza sativa L.) collected from arsenic affected area of 28Bangladesh. The agricultural soil of study area has become highly contaminated with 29 arsenic due to the excessive use of arsenic-rich underground water (0.070±0.006 mg l -1 , 30 n=6) for irrigation. Arsenic content in tissues of rice plant and in fractions of rice grain of 31 two widely cultivated rice varieties, namely BRRI dhan28 and BRRI hybrid dhan1, were 32 determined. Regardless of rice varieties, arsenic content was about 28 and 75 folds higher 33 in root than that of shoot and raw rice grain, respectively. In fractions of parboiled and 34 non-parboiled rice grain of both varieties, the order of arsenic concentrations was; rice hull 35 > bran-polish > brown rice > raw rice > polish rice. Arsenic content was higher in non-36 parboiled rice grain than that of parboiled rice.

Abstract:23 Phytoremediation, a plant based green technology, has received increasing attention after the 24 discovery of hyperaccumulating plants which are able to accumulate, translocate, and 25 concentrate high amount of certain toxic elements in their above-ground/harvestable parts. 26Phytoremediation includes several processes namely, phytoextraction, phytodegradation,

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COVID-19, the global threat to humanity, shares etiological cofactors with multiple diseases including Alzheimer’s disease (AD). Understanding the common links between COVID-19 and AD would harness strategizing therapeutic approaches against both. Considering the urgency of formulating COVID-19 medication, its AD association and manifestations have been reviewed here, putting emphasis on memory and learning disruption. COVID-19 and AD share common links with respect to angiotensin-converting enzyme 2 (ACE2) receptors and pro-inflammatory markers such as interleukin-1 (IL-1), IL-6, cytoskeleton-associated protein 4 (CKAP4), galectin-9 (GAL-9 or Gal-9), and APOE4 allele. Common etiological factors and common manifestations described in this review would aid in developing therapeutic strategies for both COVID-19 and AD and thus impact on eradicating the ongoing global threat. Thus, people suffering from COVID-19 or who have come round of it as well as people at risk of developing AD or already suffering from AD, would be benefitted.