Aim: To study difference in self-concept, physical self-concept, and time perspective between the students with multiple sclerosis (MS) and healthy students. Material and Methods: The study population of this descriptive-correlational study consisted of the students living in Shahrekord of whom 200 people (100 males and 100 females) were selected by multistage cluster sampling. Data were collected by Sarasota's Self-concept Scale, Zimbardo Time Perspective Inventory, and a researcher-developed physical self-concept questionnaire. Results: Patients' average scores on the subscales negative past, deterministic current, purposeful future, and transcendental future of the variable time perspective were higher than healthy students'. The average scores on the variable self-concept, the subscales physical, social, mood, academic, and rational of the variable physical self-concept, and the subscale positive past from the variable time perspective were significantly higher in healthy students than patients. Overall, there were significant and inverse correlations between self-concept, physical self-concept, and positive past, between self-concept and negative past, deterministic current, and hedonistic current as well as between physical self-concept and negative past, deterministic current, and transcen-dental future. There were also significant and direct correlations between negative past, deterministic current, and hedonistic current as well as between self-concept and positive past, purposeful future, and transcendental future. In the patients, the females' scores on self-concept, purposeful future, and transcendental future were significantly higher than males', and males' scores on physical self-concept were significantly higher than females'. In healthy students, the average scores on self-concept, positive past, hedonistic current, and purposeful future were significantly higher in females than males. Conclusion: Findings indicated that overall, the people with MS, compared to healthy people, have negative self-concept and self-concept as well as negative attitudes toward their own social relationships and moods. They also consider their intelligence and talent to be lower and more negative compared to those of healthy people, have negative attitudes toward their past, and consider their lives to be deterministic.
