This study was carried out in the nephrology unit to Rajshahi Medical College Hospital, Rajshahi during the period 2003-2005. Renal biopsy was done in one hundred adult patients with Nephrotic syndrome to evaluate the histopathological pattern. Mesangioproliferative GN was the commonest underlying cause which is found in 36 (40%) cases. MPGN is followed by minimal change disease in 22 (24.44%), membranous GN 16 (17.77%), membranoproliferative glomerulonephritis 12 (13.33%), Focal segmental glomerulosclerosis 3 (3.34%) and IgA nephropathy 1 (1.12%) cases. This is concordant with other studies.

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To identify the causes of haemoptysis and to diagnose the diseases clinically and cost effective laboratory investigations in our situation. Fifty consecutive cases of haemoptysis admitted at Rajshahi Medical College Hospital, Rajshahi during 2000-2001 were prospectively studied .Pulmonary tuberculosis was the commonest found in 19 (38%) cases. Tuberculer bacilli could be isolated in 5 (26.31%) of the cases. Eight (16%) patients were mitral valvular diseases . Bronchial carcinoma was 4(8%) of the series. Three patients (6%) were lung abscess. Six patients (12%) had bronchiectasis. Five patients (10%) had pneumonia. Remaining five (10%) patients were miscellaneous aetiology. In the present series it has been found that pulmonary tuberculosis and mitral valvular disease comprise 54% of the cases. Chest X-ray and sputum examination were found to be the two most useful investigations necessary for aetiological diagnosis of haemoptysis. Within limited resources the aetiological diagnosis of haemoptysis can easily be done in the majority of cases by doing chest X-ray and sputum examination in our country.

Relapsing polychondritis is a rare, severe, episodic and progressive inflammatory disorder of unknown aetiology and autoimmune pathogenesis, causing recurrent inflammation of involving cartilaginous structures, predominantly those of the ears, nose, and laryngotracheobronchial tree. Rarity of this disease, array of many possible presenting symptoms, lack of specific diagnostic investigation and episodic nature often causes significant delay in diagnosis. We are reporting a 55 year old woman presenting with recurrent episodes of pain, swelling, redness of nose, and both ear resulting in depressed nasal bridge and floppy pinna. Relapsing polychondritis was diagnosed and she was treated with systemic corticosteroid successfully.DOI: http://dx.doi.org/10.3329/jom.v15i1.19881 J Medicine 2014; 15: 80-83

Background: Gallstone disease one of the major health problems and causes of morbidity in Bangladesh as well as worldwide. Ursodeoxycholic acid is a bile acid which is used for dissolving gallstones.Objectives: To observe dissolution of gallstones among the patients of gallstone disease by use of ursodeoxycholic acid. Methods: It was a cross-sectional observational study carried out in the Department of Medicine, Rajshahi Medical College Hospital, Rajshahi from July, 2014 to June, 2016. According to inclusion and exclusion criteria 12 people having gallstone disease were selected whose stone size were <10mm and were treated withUrsodeoxycholic acid (Dosage of 8-12mg/kg/day). Thorough history, physical examination along with Ultrasonographical assessment were done for this study.Results: Complete gallstonedissolution with Ursodeoxycholic acid occurred in 08(66.67%) cases whereas dissolution did not occur in 04(33.33%) cases among the patients of gallstone diseases.Conclusion: In this study, complete dissolution of Gallstones (<10mm) occurred in 66.67% patients.TAJ 2014; 27(2): 27-29