Background: Covid-19 disease emerged nearly two and a half years back and lead to a pandemic whose severity ranged from a mild to a severe disease, those who were vaccinated had an asymptomatic infection or had a mild variety of the disease. Objective: We aimed to compare the serum antibody levels in vaccinated and unvaccinated subjects. Method: Antibody levels in vaccinated and unvaccinated subjects were measured and compared. Results: Of the 200 subjects, the vaccinated subjects had a higher antibody level (mean 5616.13 AU/ml) against the unvaccinated subjects (mean 181.22 AU/ml), hence a greater protection against the Covid.