Background: Modern technology has made a radical change in our life. The internet is one form of that technology that invades our life with its applications. Variant social media has become an essential part of our daily routine. Objectives: This study aims to map social media usage among medical students and describe the relationship between social networking sites and social and academic behavior. Method: A Cohort prospective study using a predesigned paper-based, pilot-tested, and selfadministered questionnaire. The study was conducted in the academic year 2018-2019 on the fourthyear medical students in the faculty of medicine at Menoufia University. A total of 211 fourth grade medical students were randomly selected. Results: The average time spent on the internet is 4 -6 hours daily mainly for communication. There was a high statistically significant relation between internet browsing generally and Social media specifically and the score of the behavior changes. There were high scores of students` behavior accompanying the high use (P <0.001). Conclusion: Social channels are widely used, and they influence the behavior of their users. So, we recommend further studies to determine the type of affected behavior.