As from the last eras number of the revolution in the drug delivery technologies have been seen to attain the targeted drug delivery or site specific action of the drug. The prospects of the drug delivery by using biomimetic nanoparticles such as virosomes is an motivating research & development field as showing targeted action by fusion with the targeted action by fusion through target cell. It can be engaged as vehicle & vaccines furthermore victory of virosomal drug delivery depends on the method used to make the encapsulated bioactive materials, characterization & formulation of finished products. They are reconstituted viral envelopes that can be conveyance of different macromolecules as these are biocompatible, biodegradable, nonautoimmunogenic. Virosomes denotes such a unique system for presentation of antigen to immune system. Peptides, nucliecacid & medications such as antitoxins, anticancer agents &steroids can be encapsulated. This review focus on various aspects of Virosomes, such as Structure of Virosomes Component, Advantages, disadvantages, Method of preparation, Characterization, recent Patents and applications of Virosomes etc. Key words: Neurodegenerative, Nonimmunogenic, Endolysosomal, Cryoprotectants, Applications.

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