This research aims to identify socio-economic and sanitarian impacts of the Kamuina Nsapu insurrection on the livelihood of rural populations in the territory of Miabi. It also seeks to understand the resilience mechanisms developed by the local community faced this psychosocial shock. Therefore, the household survey and structured interview were used for collecting data through the villages of Katende, Miketa and Tshilundu. In addition, the analysis method was explored for data processing by using R 3.5 software. After investigation, it was found that the Kamuina Nsapu phenomenon remains the major shock recorded by the respondents. This humanitarian shock had driven to socio-economic impacts: decreasing of livelihoods for local community which is linked with the increasing of insecurity and vulnerability in this rural area, on one hand. On the other hand, the sanitarian impact is namely the increase of severe malnutrition at around of 36.6%. Faced this mechanism, the local community are resorting more to migration as the main resilience mechanism to ensure their survival. Therefore, it is necessary to call on all stakeholders in this territory for helping local community to overcome this humanitarian tragedy.