Remdesivir (RDV) prodrug can be metabolized into a triphosphate form nucleotide analogue (RDV-TP) to bind and insert into the active site of viral RNA dependent RNA polymerase (RdRp) to further...
The SARS-CoV-2 RNA dependent RNA polymerase (RdRp) serves as a highly promising antiviral drug target for Remdesivir analogue (RDV-TP or RTP). In this work, we mainly employed alchemical all-atom simulations...
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