We have developed aconcise method of synthesizing racemic arylpropanoic acids,which have been widely used as nonsteroidal anti-inflammatorydrugs (NSAIDs).T he synthesis involves only four steps from commercially available benzaldehyde.T he synthesis incorporatesa nu nprecedented reduction reaction, conversionof3 -hydroxy-2-arylpropenoic acid ethyl esterto2-arylpropenoic acid ethyl ester by BH 3 ·THF.T he reduction reaction has been investigatedand optimized.
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