S almonellosis remains a major public health issue worldwide with a huge global burden of morbidity and mortality especially in developing countries (Sodagari et al., 2020). It is estimated to cause 93.8 million human infections and 300,000 deaths annually (WHO, 2020) besides causing a major challenge in the global poultry industry. It is well known that human salmonellosis is associated with the consumption of different kinds of food, in particular poultry and poultry products (Favier et al., 2013). Other routes of infection between individuals are represented by the fecal-oral route and contact with infected pets through contamination of food and drink by the hands, thus disease outbreaks can occur (Munck et al., 2020).

The objective of the present research is to assess the performance of re-used mariculture system on growth rate and percent survival of S. aurata and D. labrax fish; more over to evaluate water quality, which affects fish production. The results revealed that the degree of re-used sea water was 96.7% which equal 65 L daily and the new water added /Kg fish was 8.8 L/Kg juvenile S. aurata daily and 3.28 L/Kg fries D. labrax daily.