Binary and ternary systems composed of dapsone, sulfobutylether-β-cyclodextrin (SBE-β-CD), β-CD and egg phosphatidylcholine (EPC) were evaluated using 1D ROESY, saturation transfer difference NMR and diffusion experiments (DOSY) revealing the binary complexes Dap/β-CD (K(a) 1396 l mol(-1)), Dap/SBE-β-CD (K(a) 246 l mol(-1)), Dap/EPC (K(a) 84 l mol(-1)) and the ternary complex Dap/β-CD/EPC (K(a) 18 l mol(-1)) in which dapsone is more soluble.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.