34 Microsporum canis, 13 M. gypseum and 12 T. rubrum). A broth microdilution method was used following the recommendations of the NCCLS document M38-P with some modifications. RESULTS. Terbinafine was the most active agent against the dermatophytes studied (MIC 90 Յ 0.03 g/ml), followed by voriconazole (MIC 90 , 0.25 g/ml) and itraconazole (MIC 90 , 0.5 g/ml). Fluconazole was the least active antifungal agent. The most susceptible species was M. canis. CONCLUSIONS. Voriconazole was found to have effective activity against dermatophytes.

No abstract