Surfactant application via a thin endotracheal catheter without intubation seems to be a beneficial therapy for preterm infants with slight and mild degree of RDS. This new method of surfactant application was associated with a lower prevalence of intubation and MV and better pulmonary outcome than implementation of traditional surfactant therapy (INSURE) and MV. Prospective randomized controlled trial is required.

A case of 25- years-old female with NET deriving from Meckel's diverticulum is described. The patient had one year history of dermatological skin problems. Ultrasound examination of abdomen performed because of arterial hypertension, revealed multiple hepatic lesions, which was confirmed in contrast enhanced CT. The typical contrast enhanced metastatic lesions in CT and elevated levels of chromogranin A suggested NET of unknown origin. SRS with 99mTc-HYNICTOC was perform for primary tumor localization, and revealed liver and paraaortic lymph nodes metastases, but no sign of primary tumor location. As a next step for primary tumor localization 68Ga-DOTATATE PET/CT was done, which revealed focus of increased uptake in small intestine considered to be the primary tumor site. The imaging and clinical history of patient was discussed on ENETS Tumor Board. Due to location of primary tumor in the small intestine with no anatomical changes in CT, laparotomy guided with gamma probe after 68Ga-DOTATATE injection was performed. During surgery procedure, the primary tumor was hardly palpable in the tip of Meckel's diverticulum, confirmed by gamma probe. After surgery, tandem peptide receptor radionuclide therapy (PRRT) was started. Patient received 4 doses of 90Y/177Lu-DOTATATE with total activity of 360 mCi (13.32 GBq). The three months follow up 68Ga-DOTATATE PET/CT had shown stable disease of patient. The presented case showed importance role of multidisciplinary team cooperation in patient management. Use of RGS is essential in cases like presented, when the tumor cannot be localized only by surgical palpation.

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e91showed in the ultrasound a heterogeneous endometrium with 17 mm thick without identification of any embryonic structures and no fluid in the Douglas' pouch. A week later her ␤-hCG in the serum was of 4177 mUI/mL and the pelvic ultrasound shows an image within the fundus/left horn compatible with an ectopic pregnancy. The patient was submitted to diagnostic laparoscopy followed by left cornual resection and left salpingectomy by laparotomy. Histological studies of the fragment showed signs of decidualization and tissue invasion by trophoblast. 2. 27 year old woman, G4P1 (cesarean section in 2014), sent by the Reproductive Health Consult with the diagnosis of ectopic pregnancy. The ultrasoud showed near the left horn of the uterus a econegative image with peripheral vasculature and deciduous reaction with about 31 mm × 23 mm.Conclusion: The described clinical cases were treated surgically, reducing the likelihood of relapse, and both cases had only as risk factor a history of previous pelvic surgery. None of the patients had acute abdominal hemorrhage or was ever hemodynamically unstable.http://dx.

Objectives: Endocervical curettage (ECC) together with the dilatation and curettage of the uterine cavity (D & C) is routinely performed in everyday clinical practice. The aim of this study is to assess the rationale of the performance of ECC prior to D & C in indications other than abnormal uterine bleeding (AUB). Material and methods:Case histories of 736 patients after ECC performed in the 1 st Department of Obstetrics and Gynaecology, Medical University of Warsaw, were analyzed retrospectively, the indications for the procedure -age, menopausal status, parity, procedure operator's experience -as well as the result of the histopathology examination were taken into account. Three groups of patients were distinguished based on the indications for the procedure. Results:In 645 (87.6%) of cases normal histopathology results were obtained. 40 (5.4%) cases were abnormal. 31 cases of uterine cervix dysplasia were disclosed (CIN 1-20; CIN 2-5; CIN 3-6), 8 cases of endometrial cancer and 1 case of cancer of the uterine cervix were disclosed. In 51 (7%) of cases tissue material for histopathology examination was not obtained. In patients where ECC and D & C were performed due to indications other than abnormal bleeding from uterine cavity, no abnormal results were revealed. In addition, in this group the highest number of non-diagnostic ECCs was reported (11.59%; p < 0.05). Conclusions:In the case of endometrial biopsy for indications other than AUB routine ECC prior to D & C need not be performed.