Mild conditions are described that allow the palladium-catalyzed cross-coupling of C(alpha)-alkynylated glycine with a wide variety of electron-rich and electron-poor aryl and heteroaryl halides in aqueous media.

[reaction: see text]. N-propargylamino acids and peptides including them can be efficiently derivatized in aqueous media with a wide variety of (hetero)aryl halides by cross-coupling reactions catalyzed by palladium on carbon (10% Pd/C).

A new ligand, L, bearing two ethyl acetate pendant groups has been synthesized by reaction of the precursor ligand L A with ethylbromoacetate. The coordination capability towards transition [Mn 2ϩ , Ni 2ϩ ], post-transitional [Zn 2ϩ and Cd 2ϩ ] and Pb 2ϩ ions has been investigated starting from the hydrated perchlorate salts of the metals. The new ligand L and the metal complexes obtained were characterized by elemental analysis, FAB MS,

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A new pendant‐armed macrocyclic ligand, L1, bearing four pyridyl pendant groups has been synthesized by N‐alkylation of the tetraazamacrocyclic precursor L with 2‐picolyl chloride hydrochloride. Metal complexes of L1 have been synthesized and characterized by microanalysis, MS‐FAB, conductivity measurements, IR, UV‐Vis, 1H and 13C NMR spectroscopy and magnetic studies. Crystal structures of the ligand L1 as well as of the complexes [Ni2L1](ClO4)4·5CH3CN and [Cu2L1](ClO4)4·4.5CH3CN have been determined by single crystal X‐ray crystallography. The X ray studies show the presence of two metal atoms within the macrocyclic ligand in both metal complexes showing five coordination arrangement for the metal ions.