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Graphical abstract

The method developed herein is simple and can be used for market survey and quality control of functional cosmetics.

α-bisabolol, and ascorbyl tetraisopalmitate, respectively. The calibration curves showed good linearity with determination coefficients (R 2 ) ≥ 0.999. The mean recoveries were ranged between 89.8 and 103.9 % with relative standard deviations (RSDs) <5 %. The intra-and inter-day precision was <2 %. The limits of detection (LODs) were 0.03, 0.4, and 4.02 μg mL −1 for glabridin, (−)-α-bisabolol, and ascorbyl tetraisopalmitate, respectively. The method was successfully applied for monitoring 11 market samples, in which glabridin was quantified in the range of 17.5-25 mg 100 g −1 , (−)-α-bisabolol in the range of 25.1-677 mg 100 g −1 , and 140.6-291.5 mg 100 g −1 for ascorbyl tetraisopalmitate. The proposed analytical method is simple, sensitive, and versatile and can be used for the quantification of lipophilic compounds in cosmetics in a single chromatographic run.

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