Crab samples, both male and female specie, were purchased from fishermen at the Ojo Rivers, Lagos, Nigeria. The samples separated into abdomen, muscle tissue, and thorax were oven dried at 80°C for 3 days. The dried samples were then pulverized in a clean acid-washed mortar and pestle. Approximately 1.00 g each of the pulverized samples was weighed and Zn, Cr, Pb, and Cd were determined in the solution of the aqua regia digested samples by means of AAS (Buck Scientific 210 GVP model).The results obtained showed Zn metal to be consistently higher in all the female parts compared to the male with values of 12.92 ± 3.65 lg/g to 16.03 ± 1.08 lg/g and 9.33 ± 1.77 lg/g to 15.75 ± 1.02 lg/g, respectively. Mean values of 0.39 ± 0.09 lg/g and 0.22 ± 0.02 lg/g cadmium were found in the abdomen and tissue of the male crab as against 0.35 ± 0.07 lg/g and 0.17 ± 0.07 lg/g in the female crab. The tissues of both species have comparable value of chromium. Lead was below the detection limit of 0.05 lg/g in the tissues of male crab but the female tissue contained 0.83 ± 0.13 lg/g and in other parts identified, lead was consistently higher than the 2.00 lg/g permissible level of WHO in foods. A simple pair t-test did not demonstrate any significant difference in the distribution of metals between the male and female crabs. The coefficient of variation (CV) calculated for each metal with respect to the studied parts showed Pb to be widely distributed (56.23-89.54%) while Cr did not vary widely (4.17-8.20%).