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BackgroundExtremely low-frequency magnetic fields (ELFMF), have been reported to produce a variety of biological effects, interfere with the activity of the brain and may cause behavioral and cognitive disturbances. Some efforts have been made to investigate the incidence of ELFMF on human health and animal physiology and behavior. Materials and methods30 male rats were completely divided into 3 groups (2 experimental and control). Exp1, group that were exposed EMFs (50 Hz ferqency, 2 mT intensity) for 20 minutes. Exp2, group that were exposed EMFs (60 Hz frequency, 2 mT intensity) for 20 minutes. For similar conditions control group were situated into set of EMFs for 20 minutes. Sapatial memory was done with Morris water maze (6 days, 4 trails). ResultsThe results show that exposed to EMFs(50 Hz&60 Hz frequency, 2 mT intensity) are significantly better in practice related to spatial memory in comparison with control group. ConclusionsOur results demonstrate that exposed ELFMF are significantly better in practice related to spatial memory in comparison with control group. AcknowledgementsWe thank Azad University of Mashhad for Support.

BackgroundThe existence of an endocannabinoid system in the central nervous system that consists of G protein-coupled CB1 cannabinoid receptor and endocannabinoids, including arachidonylethanolamide and anandamideand 2-rachidonoylglycerol, has gained general acceptance. Recent reports suggest that this system may serve several physiological functions thus, this research has tried to examine the research is the role of Tetrahyrocannabinol on learning process and spatial memory consolidation. Materials and methods40 male wistar rats (3-4 month, 320-260 g) were completely divided into 4 experimental groups and control group. Cannabis sativa seed was extracted with Soxhlet apparatus. To test spatial memory, Morris water mazemaze (7 days,4 trails) was used experimental groups with 50 mg.kg -1 , 100 mg.kg -1 , 150 mg.kg -1 , 210 mg.kg -1were injected in the peritoneal (IP) respectively and after one hour of injection spatial memory was done. ResultsThe results show that experimental groups (50 mg.kg -1 , 100 mg.kg -1 , 150 mg.kg -1 doses), for learning time have significant level deduction in the comparison of controlgroup (p < 0.05), but experimental group with 210 mg.kg -1 dose has not significant level in the comparison of control group (p < 0.05). ConclusionsThe research findings show that, Cannabinoid components Injected dose dependent, can be effective on memory and learning processes in Morris water maze test. AcknowledgementsWe thank Dr Heravi and Mr Kazaemi form money support and Azad university of Mashhad, Department of PHysiology from prepare Maze and Materials.

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