The present investigation was conducted to evaluate the effect of Citrus maxima fruit peel supplementation in alloxan-induced diabetic rats. Diabetes was induced in male Long Evans rats by intraperitoneal injection of alloxan monohydrate (90 mg/kg body weight). Blood glucose level, oral glucose tolerance, and liver enzyme markers were evaluated. Moreover, histopathological examinations were also conducted using in liver sections to examine inflammation and fibrosis in the liver. Alloxan administered animals showed significant body weight loss and poor glucose tolerance. Alloxan administration also increased the liver marker enzymes' activities and increased oxidative stress parameters compared to control rats. Citrus maxima fruit peel supplementation for 21 days significantly (p < 0.05) reverted the glucose intolerance and liver enzymes activities to near normal levels. Moreover, Citrus maxima fruit peel supplementation prevented oxidative stress in liver of alloxan-induced diabetic rats. Our investigation also showed that alloxan administration in rats causes inflammatory cells' infiltration and fibrosis in the liver which is ameliorated by Citrus maxima fruit peel supplementation. Our investigation suggests that Citrus maxima fruit peel supplementation can ameliorate alloxan-induced diabetes and its complications. The antioxidant properties of the fruit probably play a major role in the observed effects.
The nanotechnology‐based nanofluid has extraordinary prospects in heat transfer engineering. Analysis of these applied nanofluids can yield the appropriate combinations of various useful physical parameters. In the present study, the incompressible boundary layer flow of a nanofluid in the presence of the variable chemical reaction, temperature‐dependent viscosity, hydromagnetic force, and the radiation past an infinite vertical plate has been investigated. The governing nanofluid equations are simplified to ordinary differential equations, which are solved using the function bvp4c from MATLAB. The effects of the physical parameters including the similarity parameter, magnetic field, two dimensionless constant temperatures, Schmidt number, local Grashof number, radiation parameter, local chemical reaction parameter, kinematic diffusion parameter, and temperature‐independent kinematic diffusion parameter on the velocity, temperature, concentration and the local Nusselt number are demonstrated. The results show that as the magnetic field parameter increases, the heat transfer decreases, and the increase of the radiation parameter yields the opposite effect. The kinematic diffusion and the chemical reaction parameters greatly stimulate the concentration of nanofluid and reduce the heat transfer.
The tourism is the dynamic and earning source of foreign currency in SAARC region. In regarding Bangladesh it is one of the prospective sectors that can contribute to our economy. In this paper, we forecast the international visitor’s arrival in SAARC countries and compare it with Bangladesh. In addition, we have discussed the factors that influenced the visitors to visit this territory. The key factors are infrastructure, retail industries, diversification, marketing and media, quality control, affiliation benchmark, and security and safety (Y. Benchabane, 2014). Assess the performance of Bangladesh in these key factors and comparing with other countries of SAARC region.
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