Objective: The principal aim of this work is to describe the different measures taken by three departments involved in treatment of patients followed for cancer during the SARS pandemic COVID-19. Method: A prospective study, using anonymous questionnaire, among the medical and paramedical team of hematology, medical oncology and radiotherapy during the pandemic. Results: The staff nursing was mainly constituted by a paramedical team (71,5%), with female predominance at 77,8%, sex ratio F/M=3,5, the high majority range age of the team was 30-45 years, living as a couple (52,4%). During the Covid pandemic, all our staff used bib, normal bib (76,2%), FPP2 (20,6%) combined bib (FFP2/normal) in 28,6% with visor in 6,3%. The duration of using of the same bib was variable, it has been used for 12h and more in 52, 5% and during 4h, 6h and 8h in 12,5%, 7, 5% and 27,5% respectively. For the out work management, more than half of our team return home without confinement to their family or children and only 8% have been confined on hotel. Our staff expressed a very important professional impact in 87,3% as well as in their personal lives in 85,7%.Conclusion: The vulnerability of the patients followed for cancer had obliged heath professional in this field to be even more rigorous and more vigilant on protective measures while ensuring continuity of care during the COVID pandemic. Our study illustrates that, despite the staff’s efforts of adaptation, the impact in personal and professional lives has been not negligible.