Introduction: Although giant cell myocarditis (GCM) is a rare, potentially fatal disease but its true prevalence is likely to be underestimated. GCM can lead to progressive heart failure, fatal ventricular arrhythmia and atrio-ventricular block. Case Presentation: The present report describes three cases of biopsy-proven GCM with clinical presentation including arrhythmia and heart failure. All patients were treated with immunosuppressant drugs. Conclusions: Arrhythmia and symptoms of heart failure with immunosuppression had a relative improvement in three patients.

Background: As patients turned into prone position experienced change in heamodynamics (heart rate and mean arterial blood pressure) than those on supine position, this prospective, randomized study was designed to compare the effect of PCV and Volume-Controlled Ventilation (VCV) on heamodynamics in the prone position using the Wilson frame during elective lumbar spine surgery.Conclusions: PCV provides lower Ppeak compared with VCV when the ventilator is set to deliver the same tidal volume and variable respiratory rate to maintain a constant end-tidal carbon dioxide tension in patients undergoing posterior lumbar spine surgery in the prone position using the Wilson frame.

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