The seropositivity of T. gondii has been found to be so large that it should not be ignored. It has come to the conclusion that the events in the risk group should be taken into consideration for this parasite, and awareness should be established. In recent years, this awareness has been observed, especially in neurology clinics.
AIM : To investigate the relationship between chronic use of topical antiglaucomatous drop and ocular Demodex infestation.
MATERIAL AND METHOD: This cross-sectional study included a total of 226 eyes, as both eyes of 55 patients with bilateral glaucoma and 58 control subjects. A total of 8 eyelashes, 2 each from the lower and upper eyelids of all the study participants, were taken and the samples were sent to the parasitology laboratory for analysis.
RESULTS: The mean age of the study participants was 66.48±15.19 years in the glaucoma patients, and 64.76±10.89 years in the control group. From analysis of the eyelash samples taken, ocular Demodex was positive in 55% of patients with glaucoma, and negative in 45%. In the control group, Demodex was positive in 34% and negative in 66%. Demodex infestation positivity was determined to be statistically significantly higher in patients with glaucoma (p= 0.042).
CONCLUSION: The rate of ocular Demodex infestation increases with age, and it is estimated that this rate is further increased by the use of chronic topical antiglaucomatous drops.
Toxoplasma Gondii is a zoonotic parasite showing intracellular localization. Although it doesn't select a specific region in the brain tissue, the cyst forms occurring in the chronic phase may cause behavioral changes when it is located in the brain regions related to behavior. The aim of this study is to investigate whether there is a relationship between neurodegenerative and neuropsychiatric diseases caused by antibodies transmitted to the first generation of T.Gondii infection by behavioral tests. In this study, using a total of 24 female and 6 male rats. Behavioral tests have been applied to F1 generation groups female and male. In this study, female rats with chronic T.Gondii infection have been found to have increased anxiety in open field in the first generation male offsprings and decreased locomotor activity. Increased mobility in male offsprings has been observed in the elevated plus maze test. In female offspring, it has reduced anxiety and depression.
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