Objective:To determine the effect of gender and physical activity on internet addiction in medical students.Methods:In this cross sectional, analytical study Young’s internet addiction test questionnaire was distributed to 350 MBBS students of Army Medical College, Rawalpindi. The study was conducted from January to May 2015. A dichotomous response from students regarding physical activity was obtained which was verified from the sports department of the institution. Based upon total score, internet addiction was categorized as no addiction if the score was less than or equal to 49, moderate addiction when the score was 50 to 79 and severe when the score was 80 to 100.Results:Out of 322 respondents 175 (54.3%) were males and 147 (42.7%) females with a mean age of 19.27±1.01 years. Total internet addiction score and frequency of internet addiction were similar between males and females (37.71±11.9 vs 38.63±14.00, p=0.18 and 25 vs 29, p=0.20). However, total score and frequency of internet addiction were higher in students lacking physical activity as compared to those with regular physical activity (40.37±15.05 vs 36.38±11.76, p=0.01 and 30 vs 24, p=0.01).Conclusion:Internet addiction is unrelated to gender however it is inversely related to physical activity.

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The Larger Foraminifera made a major contribution to Paleocene and Eocene biota. The microfacies and diagenetic setting of the Paleocene Lockhart Formation were analyzed in Shah Alla Ditta area, Islamabad. The Lockhart Formation is highly fossiliferous, comprising of thin nodular limestone with interbedded shale/ marl. The lower contact is unconformable with Jurassic Samansuk formation while the upper contact is conformable with Margalla Hill Limestone. Rock samples were collected from the field and thin sections were prepared and analyzed under the microscope and on the basis of detailed petrographic study three types of microfacies were identified and interpreted based on Dunham's textural classification, allochem type, fossil content and sedimentary structures. The microfacies include: LH-MF 1: Foraminiferal Wackestone/ Biomicrite Microfacies, LH-MF 2: Algal Foraminiferal Wackestone Microfacies, LH-MF 3: Mixed Bioclastic Mudstone Microfacies. A number of larger benthic foraminifera, and the lack of Planktonic foraminifera in the Lockhart Limestone, indicate shallow to deep water of restricted inner to middle shelf environment of deposition. Larger foraminifera and dasycladacena algae are the two major fossil contents present in the Lockhart Formation. Larger foraminiferal species like Lockhartia hameii and Lockhartia conditi present in the formation confirm the age of Lockhart Limestone as Paleocene. The main diagenetic fabric recognized in the limestone reveals mechanical and chemical compaction, deep burial water pressure, pressure solution and tectonics-related fracturing. The nodularity in the limestone is credited to pressure solution.

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Introduction Helicobacter pylori (H. pylori) infection is prevalent worldwide. H. pylori therapies' adverse effects can contribute to noncompliance among patients. This study aimed to assess the association between compliance to H. pylori eradication therapy and adverse effects using various drug regimens. Method We conducted an observational study from September 2017 to February 2020 in two tertiary care hospitals in patients with dyspeptic symptoms. H. Pylori detection was done by histopathological examination of gastric mucosa during upper gastrointestinal endoscopy or stool for H. pylori antigen. Patients with positive results were randomly assigned one of the nine different regimens consisting of a combination of proton pump inhibitors along with at least two antibiotics. The antibiotics used in different combinations were amoxicillin, clarithromycin, metronidazole, doxycycline, levofloxacin, and bismuth sulfate. The treatment groups received standard triple therapy with and without probiotics, sequential, concomitant, levofloxacin-based triple therapy, or sequential and bismuth-based quadruple treatments. All treatments were given for two weeks. At the end of the treatment period, patients were interviewed about completing treatment and any adverse effects they may have experienced during therapy. Data were analyzed using IBM Statistical Package for the Social Sciences (SPSS) Statistics for Windows, Version 22.0 (Armonk, NY: IBM Corp.). Results A total of 250 patients were included in the study (62% males, 38% females) with a mean age of 37 years ± 13 years (range 12-84 years). Most patients completed the treatment regimen (80.4%), and 19.6% did not complete treatment because of adverse effects (p<0.005). The levofloxacin-based, concomitant, and standard triple regimen with probiotic treatments had the highest tolerance (≥85%). Common adverse effects were abdominal and epigastric pain (11%), alteration of taste, and diarrhea (6.5%). Conclusion H. pylori eradication therapy is always a challenge. Patient compliance to the treatment can only be ensured by medicines with fewer adverse effects. In our study, levofloxacin-based triple, concomitant, and standard triple regimens with probiotics are maximally acceptable treatments.