Pendahuluan: Daun seroja (Nelumbo nucifera G.) merupakan salah satu tanaman yang berpotensi dalam bidang pengobatan, salah satunya sebagai antibakteri dalam pengobatan antijerawat. Daun seroja mengandung senyawa alkaloid, saponin, tanin, flavonoid dan steroid merupakan senyawa metabolit sekunder pada tumbuhan yang berkhasiat sebagai antibakteri. Tujuan: Tujuan penelitian adalah untuk mengetahui aktivitas antibakteri ekstrak etanol daun seroja dan krim ekstrak etanol daun seroja konsentrasi 10%, 20% dan 30% terhadap bakteri Propionibacterium acnes dan Staphylococcus aureus. Metode: Pembuatan ekstrak etanol daun seroja dengan metode maserasi menggunakan pelarut etanol 96%. Uji aktivitas antibakteri secara in-vitro menggunakan metode sumuran dengan kosentrasi 10%, 20% dan 30%. Hasil: Hasil uji aktivitas antibakteri krim ekstrak etanol daun seroja memilki zona hambat pada bakteri Propionibacterium acnes yaitu konsentrasi 10% sebesar 8,7 mm, konsentrasi 20% sebesar 12,4 dan konsentrasi 30% sebesar 14,5 mm. Dan zona hambat pada bakteri Staphylococcus aureus yaitu konsentrasi 10% sebesar 8,1 mm, konsentrasi 20% sebesar 11,1 dan konsentrasi 30% sebesar 14,1 mm. Kosentrasi yang paling baik adalah krim ekstrak etanol daun seroja pada konsentrasi 30%. Kesimpulan: Kesimpulan dari penelitian ini adalah bahwa ekstrak etanol daun seroja dapat diformulasikan dalam bentuk sediaan krim dan memiliki aktivitas antibakteri terhadap bakteri Propionibacterium acnes dan Staphylococcus aureus. Disarankan kepada peneliti selanjutnya agar melakukan fraksinasi untuk mendapatkan hasil sediaan yang lebih baik.
Chinese dates fruit are generally used by the people of Indonesia as a fruit that has a fairly good nutritional value, namely every 100 g of Chinese dates fruit contain 79 kcal of energy, 1.2 g protein, 20.23 g carbohydrates, 250 mg potassium, 21 mg calcium, 23 mg. phosphorus, 0.5 mg iron, 3 mg sodium, 10 mg magnesium, 0.1 vitamin B6 and 69 mg vitamin C. Chinese dates fruit are foods that are rich in fiber, so they can lower blood cholesterol and cure chronic constipation. In addition, Chinese dates fruit are foods with good sources of potassium. Adequate potassium intake can lower blood pressure so that it can reduce the risk of cardiovascular disease. High iron content can also prevent anemia. The purpose of this study was to determine the differences in the content of iron, potassium, calcium, and sodium in fresh and boiled Chinese dates fruit fruit, and to determine the percentage decrease in levels after boiling. The method used in this study included dry digestion, then quantitative analysis of iron, potassium, calcium, and sodium was carried out using the Atomic Absorption Spectrophotometry (AAS) method, namely iron at a wavelength of 248.3 nm, for potassium 766.5 nm, to calcium 422.7 nm, and sodium 589.0 nm. The results showed that the iron content in fresh Chinese dates fruit fruit was (0.6687 ± 0.0084) mg/100 g and boiled (0.3285 ± 0.0127) mg/100 g. Potassium levels in fresh Chinese dates fruit fruit (657.9024 ± 0.4713) mg/100 g and boiled (158.6504 ± 0.2510) mg/100 g. Calcium levels in fresh Chinese dates fruit fruit were (47.3501 ± 1.1630) mg/100 g and boiled (26.3968 ± 0.5922) mg/100 g, and sodium levels in fresh Chinese dates fruit fruit (16.1272 ± 0.1543) mg/100 g and boiled at (13.4048 ± 0.1973) mg/100 g. The percentage decrease in mineral content in Chinese dates fruit fruit after boiling, for iron was 50.87%, potassium 75.88%, calcium 44.25%; and 16.88% sodium. Statistically different test of the average mineral levels of iron, potassium, calcium, and sodium using the T distribution, it can be concluded that fresh Chinese dates fruit fruit contain higher levels of iron, potassium, calcium, and sodium minerals than boiled Chinese dates fruit.
Since 1997 until now, forest and land fires (Karhutla) in Indonesia occur almost every year. The 2015 Karhutla incident is believed to have burned 2.61 million hectares of forest and land. In 2016, even though Indonesia was hit by La Nina, forest and land fires continued to burn forest and land area of 14,604.84 hectares. Forest and land fires have a detrimental impact on the environment, social and economy. Even the problem of fires in Indonesia has caused smoke problems for neighboring countries, especially in the Southeast Asia region. The government has tried to deal with the forest and land fires both in the form of regulations and programs, but the forest fires still occur. Several studies have shown problems in handling forest and land fires, including difficulties. The government itself is aware that forest and land fire is a multidimensional problem that requires cross-sectoral coordination to deal with it. Keywords: forest fires, Indonesia, policy
Inflammation is a complex series of changes in tissue due to tissue injury caused by bacteria, trauma, chemicals, heat, and pain. Gamboge (Garcinia xanthochymus) is a fruit-bearing tree native to Southeast Asia. Plants of the genus garcinia are rich in secondary metabolites such as flavonoids, steroids, and triterpenes which have potential pharmacological activity. This study aimed to determine the anti-inflammatory activity based on the reduction in edema volume of Gamboge (Garcinia xanthochymus) stem bark. The inquiry was experimental. Through maceration, an ethanol extract of the gamboge stem was created. The animals were divided into five groups, each containing five white male rats. The test given was a suspension of gamboge ethanol extract at doses of 200, 400, and 600 mg/kgBW, a negative control of 1% Na CMC suspension, and a positive control of 2.25 mg/kgBW sodium diclofenac. Observations were made for 6 hours, and then data were analyzed using a two-way analysis of variance (ANOVA) test. The results showed that gamboge ethanolic extract was proven to have an anti-inflammatory effect in white male rats induced by carrageenan starting at doses of 200, 400, and 600 mg/kgBW, marked by a significant difference to the negative control (p<0.05). The 600mg/kgBW dose group showed no significantly different results from the positive control group (p>.05). These results concluded that the dose group 600mg/kgBW was the best dose of gamboge stem ethanol extract had an anti-inflammatory activity based on reducing the volume of leg edema of white male rats. Keywords: Asam Kandis Stem Bark; Anti-Inflammation; Male White Rats
Telang flower kombucha is proven to have various pharmacological activities, so that it can be developed as medicines, cosmetics, and its waste can be applied in agriculture as an ingredient in organic liquid fertilizer to support plant development and growth. This research aims to make hand sanitizer gel formulations and preparations with active butterfly pea flowers. Disk diffusion is used to stop gram-positive and gram-negative bacteria from growing. Post hoc analysis and one-way ANOVA were used to analyze the data. The one-way ANOVA analysis yielded results with a significance level of P<0.05, allowing the post hoc test to continue. When tested at a sugar concentration of 40%, the butterfly pea flower kombucha hand sanitizer significantly outperformed the control when it came to inhibiting the growth of the test bacteria. The best way to stop the test bacteria from growing is to use a concentration of 40%.
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