Objective: To determine the correlation of platelet indices; platelet count (PC), mean platelet volume (MPV), platelet distribution width (PDW) and platelet large cell ratio (P-LCR) with mortality in patients admitted to PICU. Study Design: Comparative cross-sectional study. Place and Duration of Study: Pediatric Intensive Care Unit (PICU) of CMH Lahore from Jun 2019 to May 2020. Methodology: Cases (mortality group) were the 81 consecutive patients who died in the PICU during the study period and fulfilled inclusion criteria. The control group comprised 81 surviving patients admitted to PICU contemporarily. Both groups' mean values of platelet indices (PC, MPV, PDW and P-LCR) were compared. Results: The mortality rate was 10.42%. Infants were the largest sub-group (45.68%) in the mortality group. Mean platelet counts were significantly low, while mean MPV, PDW and P-LCR were significantly higher in children in the mortality group compared to the control group (p-value <0.001). The correlation coefficient 'r' was -0.682,0.598,0.671 and 0.355 for platelet count, PDW, MPV and P-LCR, respectively, showing a negative correlation between platelet count and positive correlation of mean platelet volume (MPV), platelet distribution width (PDW) and platelet-large cell ratio (P-LCR) with mortality. Conclusion: Deranged platelet indices, as manifested by lower platelet count and higher values of MPV, PDW and p-LCR, were significantly correlated with higher mortality in children admitted to PICU and can be used to predict/anticipate the severity of illness.
Objectives: Obesity and high blood pressure are a well-known combination. Some studies Shows that development of hypertension in kids, teenagers, adults, which eventually led to heart disorders.We measured that blood pressure of 15 school-aged kids (ages 5–12) for 06 months, beginning in February 2019 to October 2019, while also providing Regular nutrition class and activities to assess the impact of nutrient as a routine life mediation on the kids' body composition, weight, and blood pressure school-aged children prevention programmer. In children and young children, obesity is an indisputably serious clinical problem. From 2001 to 2010, public research establish that the frequency of weighty in children increased from 6% to 14%. The consequences of adolescent obesity. Methodology: It was a cross- sectional study conducted in a hospital. The Department of Peads Medicine, P.E.M.H, Rawalpindi, Pakistan, conducted this descriptive case series. The research lasted a year. Over the course of a year, from February 2019 to October 2019, the number of children aged 5–12 years who were called in for a regular health check-up from around 100 patientswas lower normal blow cohorts than in the weighty and obese group. This shows a link between obesity and hypertension. During the hour of time spent in two groups, pulse levels decreased. Thiscould be the result of the personalized mediation or the children adjusting to the new situation. A large number of children were fearful. Results: Systolic pulse values can be seen in the results. In the standard group, fifteen children (10 M kids and 05 F kids) had circulatory strain in the 90th percentile or above in at least one calculation. In this study, 15 children (10 M kids and 5 kids F) in the intercession group reported increased cardiovascular strain in at least one estimate. Conclusion: Fat loss is the main-route antihypertensive therapy in children having high blood pressure caused by obesity. In addition, in the management of obesity-related high blood pressure, establishing heart-healthy life that take in daily bodily exercise also a food rich in berries and root vegetable, fibre, that is also low in complex carbohydrate and sweet cold drink critical. This may be problematic in children with stoutness, which is often associated with comorbid illnesses and depression and anxiety decreased flexibility. For maximum adequacy, a multidisciplinary approach is frequently expected. A small number of children will require antihypertensive medication. Both are not effective to lowering blood pressure in children. In any case, the reduced CV events observed in adults treated with RAAS inhibitors are promising. Keywords: Relationship; hypertension; obesity; children
Objectives: To assess the clinical characteristics of COVID-19 Virus disease in the pediatric population in Pakistan. Study Design: Cross-sectional study. Place and Duration of Study: Pak Emirates Military Hospital, Rawalpindi Pakistan, from Mar 2020 to Jan 2021. Methodology: All children presenting to the department with symptoms consistent with COVID-19 disease were tested for the virus. Patients who tested positive on the PCR were included in the study. Patients with non-consistent symptoms of COVID-19 and those who tested negative on the PCR were excluded from the study. All clinical data, including the age of the child, the onset of symptoms, the gap between the onset of symptoms and presentation as well as clinical symptoms, were documented on a predefined proforma. Results: A total of 106 patients were enrolled on the study. The mean age of patients was 5.6±2.5 years. The most frequent symptoms were fever (63, 59.6%) and cough (49, 46.2%). There were 3(2.9%) cases with severe or critical illness. The most frequent abnormal laboratory findings were leukopenia (29, 27.4%) and increased creatine kinase (38, 36.0%). Ground-glass opacities were observed in the HRCT chest of 17(65.3%) cases, out of 26 children diagnosed with pneumonia. The majority (70, 66%), had a positive exposure history. 88(83%) cases did not abide by the precautionary measures against the COVID-19 disease. Conclusions: The current study indicates that children usually present with mild symptoms but can present as severe diseases, as observed in this study.
Objective: The study was conducted on the incidence of meconium aspiration syndrome which is still high in the developing world and contributing significantly to the neonatal mortality. The study was aimed to know the risk factors contributing to meconium aspiration syndrome and neonatal outcome in a tertiary hospital (Punjab) Department of pediatric Medicine PAK Emirates Military hospital Rawalpindi in the Pakistan. Materials and Methods: It was a hospital based cross sectional study This descriptive case series was carried at Department of Peadiatric Medicine PAK Emirates Military hospital Rawalpindi in the Pakistan over a period of one year, from Jan 2019 to Dec 2020, involving 2820 patients; All live newborns born through meconium-stained liquor were enrolled and all the details regarding the mother and neonate were recorded. Odd’s ratio and bivariate analysis was done to assess the risk factors for meconium aspiration syndrome. Results: Out of all the deliveries 12.4% were born through meconium-stained amniotic fluid and meconium aspiration syndrome developed in 5 .6% of the neonates. Low Apgar score and premature rupture of membranes was significantly associated with the risk of occurrence of meconium aspiration syndrome. Neonates who developed meconium aspiration syndrome had mortality of 6.7% Conclusion: The Perinatal asphyxia and premature rupture of membranes were significantly associated with the development of meconium aspiration syndrome and neonates who developed meconium aspiration syndrome had high mortality.
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