Fused pyrimidine derivatives R 0515 An Investigation Leading to Preparation of Tetrahydro-quinazoline Derivatives Involving Ureidoalkylation and α-Amidoalkylation Reactions. -Multiple substituted quinazolines (VII) are synthesized and evaluated for their effect on cardiovascular (CVS) and central nervous system (CNS). -(PANDEY*, V. K.; MUKESH; KUMAR, A.; TRIVEDI, N.; Indian J.

Fused pyrimidine derivatives R 0515 Synthesis, Characterization and Antiviral Activity of 2,3-Disubstituted Quinazolones. -Title compounds (VI), (VII), and (IX) are evaluated for their antiviral activity against Japanese encephalitis virus (JEV) and Herpes simplex virus type-I (HSV-I) both in vitro and in vivo. All compounds are active against HSV-I and their in vitro activity varies from 20-56%. -(PANDEY*, V. K.; KUMAR, J.; SAXENA, S. K.; MUKESH; JOSHI, M. N.; BAJPAI, S. K.; J. Indian Chem. Soc. 84 (2007) 6, 593-597; Dep. Chem., Lucknow Univ., Lucknow 226 007, India; Eng.) -H. Haber 19-153