Introduction: Transverse myelitis is a rare disease that accured by incident 0,3%-1% Though it rare happened transverse myelitis deserve to diccus because the variant presentation that make clinical challenge to dianosis to pre-observation for upgrade’s prognosis. Case Report: we reported case of transverse myelitis that was neurology complication to rare herpes zoster virus. Woman 27 years old came by early complaint of tingling fever, pain, shiver continue on foot and the right hand. After got well, patient cameback to her disease bacause of the worst condition that cold not mover her left foot. Diagnosis transverse myelitis could stand through clinical sympton and magnetic resonance imaging (MRI) patient that came by her skin of hipopigment have to always considere the happening of transverse myelitis and lost control of defecate on neurologi observation being got paraplegi, monoparese extremitas superior, and hipoanesthesia dermatom C5 on low grade. We got observation of MRI to the level cervicothoracal that show long segment hipeintensity introdural intra medullary to the level craniovertebral junction so C5 and T2 so on that involved 2/3 spinal cord that strength described transverse myelitis. Discussion: Varicella zoster virus cou caused neurologis complication, the of transverse myelitis, of it is sign and sympton like pain, sencoric trouble, weakness on arm and foot, and the problem bladder and intestines. This symptom often occured unilaterally , Ipsilateral toward rash then become bilaterally. Intervention should the customize with pattient complaint: The implement combination asiklovir and high close steroid’s inject significantly relieve the pattient complaining but still occured paraplegi. Keywords: Transverse myelitis, HZV, neurological complication
Diazinon is an organophosphate pesticide often used by farmer. The residue of diazinon may contaminate agricultural products and if accidentally consumed in a long term, may potentially led to health problems such as kidney disorders. Shallot (Allium cepa) peel was recently proposed to help recover the kidney damage due to its high flavonoid antioxidant content. This study aims to determine the antioxidant effect of shallot peel extract in reducing oxidative stress caused by diazinon with malondialdehyde (MDA) level indicator on the kidney of Wistar rats (Rattus norvegicus). This research was a true experimental with an in-vivo posttest-only control group design. The 28 rats were divided using a simple random sampling technique. The groups were the control group (K0), the diazinon group (K1), SPEE (Shallot Peel Ethanol Extract) groups which are P1 (300 mg/kg BW), P2 (600 mg/kg BW), P3 (900 mg/kg BW), P4 (1200 mg/kg BW) and P5 (2400 mg/kg BW). At the end of the study, the MDA kidney levels was analysed using the TBARS method. Effective doses were found in 600 mg/kg BW/day, 900 mg/kg BW/day, 1200 mg/kg BW/day, and 2400 mg/kg BW/day. The optimal dose of shallot peel extract in this study was 600 mg/kg BW/day. This study showed the effectiveness of shallot peel extract in reducing kidney MDA levels in diazinon-induced Wistar rats. Keywords: shallot peel, diazinon, kidney MDA level
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