The title compound, C20H18N2O4, is a chalcone derivative of pyrazole. The pyrazole ring is inclined at a dihedral angle of 19.29 (12)° to the methoxyphenyl ring mean plane, and by 1.19 (13)° to the phenyl ring. The molecular structure is stabilized by an intramolecular O—H⋯O hydrogen bond, making an almost planar (r.m.s. deviation = 0.0243 Å) six membered ring.
A lipoxygenase inhibiting triterpene have been isolated for the first time from the ethyl acetate soluble fraction of whole plant of Solanum surrattense and the structure was assigned on the basis of 1D (1 H NMR, 13 C NMR, DEPT, NOE) and 2D NMR (HMBC, HMQC, COSY, NOESY) experiments. The biological potential of the isolated compound was performed against lipoxygenase enzyme using baicalein as a positive control.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.