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Ranunculus arvensis ( R. arvensis ) is a member of the Ranunculaceae family and is often used by advanced age women living in rural areas for the topical treatment of arthralgia, myalgia, hemorrhoid, and warts. Protoanemonin is a substance found in the fresh leaves of the plants from the Ranunculaceae family and leads to contact dermatitis. In this report, we present three cases that developed phytocontact dermatitis caused by the topical use of R. arvensis as an alternative treatment method for arthralgia and palmoplantar psoriasis.

Pseudoxanthoma elasticum (PXE) is a rare multisystemic genetic disease with dermatologic, cardiovascular and ocular involvement. PXE primarily affects the skin, and the ocular involvement is noted in almost 85% of patients. Cardiovascular complications caused by PXE often develop in adults. Since the prognosis of PXE is primarily dependent on extracutaneous organ involvement, early diagnosis of PXE is of prime importance for taking preventive measures. In this report, we present three siblings diagnosed with PXE.

Vandetanib is a multi-kinase inhibitor of epidermal growth factor receptor (EGFR), vascular endothelial growth factor (VEGFR). Most common dermatological side effects induced by vandetanib include papulopustular eruption, hand-foot syndrome, and hyperpigmentation. In this report, we present a case with metastatic medullar thyroid carcinoma who developed vandetanib-induced photoallergic dermatitis.