Eradication of H pylori decreases serum homocysteine even in patients who do not exhibit gastric mucosal atrophy. It appears that the level of homocysteine in serum is related to a complex interaction among serum vitamin B(12), serum folate and erythrocyte folate levels.

Aim:To determine the correlation of Helicobacter pylori infection with peripheral blood neutrophil/lymphocyte ratio (NLR) and mean platelet volume (MPV).Materials and methods:The NLR, MPV, platelets, leukocytes, neutrophils, and lymphocytes were calculated and the differences between groups were investigated.Results:A total of 199 patients were included in the study. Neutrophil/lymphocyte ratio was statistically lower in H. pylori-positive patients than in H. pylori-negative patients (1.94 ± 0.79 vs 2.67 ± 2.35 respectively, p = 0.04). There was no significant difference between H. pylori-negative patients and H. pylori-positive patients of severe intensity in terms of MPV. However, peripheral blood lymphocytes and platelets were statistically significantly higher in H. pylori-positive patients of severe intensity (lymphocytes 2150 ± 826 vs 2954 ± 2436 respectively, p = 0.000 and platelets 258247 ± 69494 vs 265611 ± 113397 respectively, p = 0.02) compared with H. pylori-negative patients.Conclusion:A moderate increase in the intensity of H. pylori does not lead to a significant change in MPV as measured by hemogram; however, it gives rise to a statistically significant fall in NLR. Presence of severe H. pylori-positive intensity leads to a statistically significant increase in peripheral blood lymphocytes and platelets compared with H. pylori-negative patients.How to cite this article: Guclu M, Agan AF. Association of Severity of Helicobacter pylori Infection with Peripheral Blood Neutrophil to Lymphocyte Ratio and Mean Platelet Volume. Euroasian J Hepato-Gastroenterol 2017;7(1):11-16.

ÖzBu ara tırmada de erler e itimine yönelik olarak Türkiye'de gerçekle tirilen ara tırma sonuçlarının de erlendirilmesi amaçlanmı tır. Bu çerçevede "de erler e itimi" anahtar kavramı ile ilgili olarak internet ve kütüphane ortamında tarama yapılmı amaca uygun olarak bulunan makale ve tezler betimsel analiz yöntemiyle incelenmi tir. De erler e itimini ö rencilerin geli imine olan etkileri açısından de erlendiren ara tırmalarda; de erler e itiminin çocuklarının sosyal, bili sel, duyu sal ve ahlaki anlamda etkileri ara tırılmı tır. Bunun yanında de erler e itiminin çocukların demokratik tutumlarına olan etkileri ile öz düzenleme becerilerine olan etkileri ile ilgili konulara yer verilmi tir. De erler e itiminde kullanılan araçlarla ilgili ara tırmalarda; hikâyelerin, de i ve semahların, gazetelerin, okullara tavsiye edilen yüz temel eserin, atasözlerinin, farklı yazarlar tarafından ele alınmı eserlerin, çizgi filmlerin ve duaların de erler e itimi açısından incelenmesi yapılmı tır. Bunun yanında de erler e itimini ö retmen görü lerine ve programın etkilili ine göre ele alan ara tırma sonuçları da bulunmaktadır. Anahtar Kelimeler:De erler E itimi, Lisansüstü Tezler, Ara tırma Sonuçları, De erler E itimi Programı. AbstractIn this study, an evaluation of results of studies was aimed at, conducted on values education in Turkey. Within this framework, a survey of the key concept "values education" was conducted in the Internet and library, and articles and dissertations which were appropriate for the purpose of the study were examined by the descriptive analysis method. In the studies, which consider values education from the viewpoint of the effects on the development of students, effects of values education on students' social, cognitive, affective and moral development were investigated. In addition to this, there are studies on effects of values education on children's democratic attitudes and their self-regulation skills. In the studies on instruments used in values education, examination of and effects of values education on stories, sayings and semahs, newspapers, one hundred basic books recommended in schools, proverbs, books considered by different authors, cartoons and prays were addressed. In the studies, which address values education by teachers' views, it is seen that subjects such as how teachers can teach values education effectively and which values they prioritize.

A mutation in the methylenetetrahydrofolate reductase (MTHFR) gene is known as one of the causes of hyperhomocyteinemia. The oxidation products of homocysteine can initiate lipid peroxidation, which has a central role in the pathogenesis of nonalcoholic fatty liver disease (NAFLD). We aimed to assess the possible role of the MTHFR C677T mutation in the progression of simple steatosis to an advanced form of NAFLD. Thirty-four patients with NAFLD diagnosed by histologic analysis and 282 healthy controls were included in the study. The discrimination of nonalcoholic steatohepatitis (NASH) from another NAFLD was made by NAFLD activity score (NAS), and a NAS>or=5 was considered NASH. Patients with either NASH or nonalcoholic fatty liver (NAFL) and controls were evaluated for frequency of the MTHFR C677T mutation. The frequency of the MTHFR C677T mutation was 53.5% (CT, 44.7%; TT, 8.9%) in controls and 41.5% (CT, 37.7%; TT, 3.8%) in patients (odds ratio [OR], 0.62; 95% confidence interval [CI], 0.34-1.12). There was no statistical difference in the frequency of this genotype between patients with NAFL and those with NASH (36% [CT, 28%; TT, 8%] vs 46.4% [CT, 46.4; TT, 0%]; OR, 0.65; 95% CI, 0.22-1.96). According to this study, the MTHFR C677T mutation does not seem to be a risk factor for the progression of NAFL to NASH.

No abstract