Abstract:In this study, spherical silver nanoparticle (AgNP) was produced by sustainable chemical method i.e. glucose reduction method and it was utilized to analyse the bactericidal effect against the pathogens of clinical importance -E. coli (ATCC 10536) and Enterobacter sp., KL46 by membrane destabilization and protein leakage analyses. Minimum inhibitory/bactericidal and antibiogram analyses reported that 20ng/ml was enough to inhibit/kill bacterial cells. Even 20ng/ml concentration of AgNPs was found to destabilize membrane and lead to protein leakage from bacterial cells.

This comparative study was conducted from April 2018 for a period of 1 ½ years at ESIC MEDICAL COLLEGE & PGIMSR, K.K.NAGAR, CHENNAI -78 for a total of 50 patients who were diagnosed with Great saphenous varicose veins with perforator incompetence .Patients underwent open subfascial perforator ligation or subfascial endoscopic perforator ligation. The observation and inference is noted in this presentation.

This is a presentation of four rare and interesting cases of bilateral breast cancer. The cases vary from Synchronous double primary carcinoma breast, bilateral infiltrating ductal carcinoma, bilateral synchronous metastatic carcinoma and metachronous breast carcinoma. The incidence of developing either primary or metastatic carcinoma in the other breast is increased in patients who already have carcinoma in one side and mammography contributes greatly to the detection of these lesions. (1) It is of significant prognostic value and important in deciding the clinical management based on the classification whether it is a primary or a secondary lesion.

This comparative study was conducted at ESIC MEDICAL COLLEGE & PGIMSR, K.K.NAGAR,CHENNAI -78 for a total of 50 patients who were diagnosed with Great saphenous varicose veins with perforator incompetence for a period of 18 months from April 2018. Patients underwent open subfascial perforator ligation or subfascial endoscopic perforator ligation in a 1: 1 ratio by alternate allocation method. Odd numbered patients were treated by subfascial endoscopic perforator surgery and even numbered patients were treated by open subfascial perforator ligation . The observation and inference is noted in this presentation.