Japanese or kyuri cucumber was more longer, softer and suitable for salads than local cucumber. Cultivation techniques for increasing the production of cucumbers can be done by manipulating growth by the pruning and application of manure especially chicken manure which is more complete than other manures. The study was conducted at Deli Serdang regency in polybag from January until April 2021. The result showed that the application of chicken manure has a significant on fruit weight per plant and root weight at a dose of 600 g/polybag. Pruning the main stem shoots has a real effect on the weight of the fruit. There is an interaction between chicken manure and pruning on fruit weight per plant. The best interaction was in combination of treatment with pruning and manure 600 g/polybag. So, cultivation of cucumbers in polybags is recommended using chicken manure 600 g/polybag and pruning on the main stem shoots.

Patients with hypertension usually experience chronic comorbidities and complications that require complex treatment (polypharmacy), which can further cause drug-related problems (DRPs) and interfere with the required clinical outcomes. This study, by using a case-control prospective cross-sectional, aimed to analyze the association between DRPs and blood pressures (BPs) of hypertensive patients admitted to Universitas Sumatera Utara (USU) hospital from July to September 2021. The incidence of DRPs was analyzed and classified according to the Cipolle classification system and reliable literature. Blood pressures of the patients were classified into controlled and uncontrolled BPs. The association between DRPs and BP was analyzed using the Chi-Square test. Most of the patients (57.5%) were female. Their mean age was 59±9.94 (years). The mean incidence of DRPs experienced by the patients was 1.78±0.79. The most frequently occurred DRPs were drug interactions. There was a significant association between the number of DRPs experienced by the patients and their BPs (p=0.02). DRPs are the contributing factor to the uncontrolled BPs of hypertensive patients.