Objectives: To evaluate the detrimental impact of smoking on oral health.Methodology: A Cross sectional comparative study was carried out on 100 patients, 50 smokers and 50 non-smokers, visitingSharif Medical and Dental College, Lahore from June 2019 to July 2020. Intra-oral examination was done using the CommunityPeriodontal Index of Treatment Needs (CPITN). Recorded data was coded, entered and analyzed using SPSS statistical Packageversion 23.ResultsThe periodontal health was significantly associated with status of smoking (p=0.001). The most prevalent periodontal problemsof smokers were periodontal pockets of 4 to 5 mm (19%) while the least (4%) had bleeding on probing. Majority of the nonsmokers(32%) had bleeding on probing. The number of cigarettes smoked in a day and periodontal health status weresignificantly associated (p=0.004). Light smokers (1 to 10 cigarettes/day) had periodontal pockets of 4 to 5mm as their biggestperiodontal problems (38%) while the least (8%) had bleeding on probing. The periodontal problem that intermittent smokers(11 to 15 cigarettes/day) predominantly had was periodontal pockets of 6 mm or more (8%) and same was the case with heavysmokers (2%).Conclusion: The main periodontal problem of smokers was periodontal pockets of 4 to 5 mm while the least was bleeding onprobing. Most of the non-smokers had bleeding on probing while none of the non-smokers had periodontal pockets. Lightsmokers (1 to 10 cigarettes/day) mainly had periodontal pockets of 4 to 5mm as their main concern. The periodontal problemthat intermittent and heavy smokers mainly had were periodontal pockets of 6 mm or more.

Objectives: This study aimed to evaluate the quality of life (QoL) of substance use disorder (SUD) patients in Khyber Pakhtunkhwa, Pakistan. Design: A cross-sectional study Setting and Participants: 500 substance use disorder patients were selected from the seven drugs rehabilitation centers of Khyber Pakhtunkhwa, Pakistan. Methods: This study was carried in seven drugs rehabilitation centers of Khyber Pakhtunkhwa, Pakistan between August 08, 2019, and December 2020. A cross-sectional study design was used to assess the QoL among 500 substance use disorder adult patients who were taking initial rehabilitation treatment via a convenient sampling technique. The WHOQOL-BREF Field Trial Version was used to measure the QoL. Results: This study found that more than 75% (very poor: 27.8%, poor: 49.8%) substance use disorder patients had a poor perception of the QoL, 81% (very dissatisfied: 33.8%, dissatisfied: 47.2%) patients were dissatisfied with the overall perception of the health. The four domains of QoL of SUDs patients were also disturbed. Conclusion: The current finding of this study illustrated that people with SUDs need more attention for their QoL and well-being. Keywords: Substance Use Disorder, quality of life, perception of the health, well-being

Gross Regional Domestic Product (GRDP) is a reflection of a region's economic growth. West Nusa Tenggara (NTB) is one of the provinces that contributes to good GRDP for Indonesia. The purpose of this research is to modeling GRDP in NTB using spatial econmetrics. The data used is the GRDP data of each district / city in NTB Province as a response variable and factors that affect the number of workers, capital value and electrification ratio as predictor variables. The results showed that there is a spatial dependence on the district / city GRDP in NTB Province on the error model so that the model formed is the Spatial Error Model (SEM) with a rho of 71.1% and an AIC value of 173.34.

With the emergence of modern genetic testing and profiling techniques, it has become imperative to assess the general public awareness and attitudes toward such developments. The public's perspective and possible responses are necessary for planning commercial, legal, medical, or healthcare initiatives. The purpose of this study was to assess the perception of the general public and professionals about the personal genome testing and genetic profiling. A questionnaire‐based survey was conducted to investigate the attitudes of 2954 adults (56.4% male and 43.6% female) from more than 120 different educational, research, and professional organizations of Pakistan. The aim of the study was to assess interest in genomic testing. The findings of this survey will feed into the larger Genome Projects in Pakistan and will be helpful for the national bioethical committee, healthcare agencies, diagnostic companies, and other institutions for making policy decisions.