The government has the responsibility to alleviate poverty and empower the deprived women, youth and persons with disability in accessing loan facilities and starting their own income generating activities. The affirmative groups introduced by the government of Kenya include the youth enterprise fund, women enterprise fund and uwezo fund. Financial sustainability of affirmative groups is important as it determines the sustainability of the funds. The current study sought to determine the effect of financial knowledge and skills on the financial sustainability of affirmative groups. The study considered the Grameen bank model and resource based theory theories to underpin the study. A cross sectional research design was adopted. The target population is 400 affirmative funded groups. The sample size is 200 affirmative funded groups. Stratified random sampling and simple random sampling were used to select the respondents. Primary data was collected using structured questionnaires. Content validity and internal consistency reliability was adopted. Data analyzed was presented using descriptive statistics and inferential statistics. The study findings indicated that financial knowledge and skills has a positive and significant effect on financial sustainability of affirmative groups in Kapseret Subcounty, Uasin Gishu. This study recommends that the management of the affirmative groups to ensure that financial skills and knowledge is paramount in to enhance financial sustainability among affirmative groups. The study will be of great benefit to policy makers of Kapseret sub county government in development of policies on financial sustainability of affirmative groups.