Among infectious diseases, tuberculosis is the second leading cause of mortality worldwide. Since 2000, Brazil is one of twenty two countries classified as "high burden countries" by World Health Organization. This study aims to report epidemiological and economic profile of tuberculosis related hospitalizations in Brazil. MethOds: Retrospective analysis of Brazilian public hospital admissions for tuberculosis was developed according to ICD-10 classification (A15-A19) as reported in Brazilian Hospital Information System (SIH/SUS) database, from January 2008 to December 2011. Epidemiological data were extracted from public reporting system. Costs represent federal reimbursement values for hospitalizations (medical procedures, exams, drugs and fees) estimated in 2013 Brazilian Real (BRL). Results: