Cytological study of body fluids has become integral part in both diagnostic and management of suspected malignant cases. The meticulous examination of body fluid for there cytomorphological properties throws light on the cause, presence of metastatic cells, typing of unknown cases, staging and prognosis of cancer.1) To study and evaluate current trends in cytological evaluation of body fluids for various pathologi­cal conditions in a tertiary care centre. 2) To analyse their frequency in relation to diagnosis.The present study is prospective type of analysis of 311 body fluids received in Department of pathology for duration of one year from Jan 2018 to Dec 2018 in our tertiary care centre. A total of 311 body fluid samples were analyzed in this study. Pleural fluid comprised of the major bulk of the study with 120 cases followed by peritoneal fluid with 100 cases. Non-malignant diagnosis was given in majority of the cases. Slight male preponderance was noted with male to female ration 1.37:1. Cytological analysis of body fluid is routine diagnostic investigation which offers definite aid to the treating physician. Preliminary body fluid analysis in resource limited setups still remains the most simple, convenient and cost effective technique in reaching to a particular diagnosis.