No abstract

There is no difference in the effect of two formulations of isotretinoin on spine bone density after 6 months of treatment. BMD increased and the small change in spine Z-score over treatment disappeared after height adjustment. Mean positive Z-scores and HAZ in the study were likely due to the exclusion of low and inclusion of high Z-score subjects.

resolving patients' complaints, we could increase the compliance to the knee braces, so improve patients' quality of life as well as delay surgery. This last point is important because of the cost of knee surgery. For instance, in 2010, KOA was responsible for 97% of initial knee replacement having a cost of £426 million in UK.